The Correlation of D- Dimer and Neutrophil Lymphocyte Ratio (NLR) Levels on COVID-19 Mortality


  • Evi Nurhayatun Department of Internal Medicine, Moewardi Hospital, Moewardi Hospital, Surakarta, Central Java, Indonesia
  • Meilani Ayu Safira Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Central Java, Indonesia
  • Arief Nurudhin Department of Internal Medicine, Moewardi Hospital, Moewardi Hospital, Surakarta, Central Java, Indonesia



COVID-19, D-dimer, Neutrophil Lymphocyte Ratio, Mortality


Coronavirus disease 2019 (COVID-19) is a disease caused by a novel coronavirus or a new type of corona virus, namely severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). D-dimer and Neutrophil Lymphocyte Ratio are parameters that can be used as a predictor of mortality in COVID-19, so this study aims to determine the relationship between D-dimer levels and NLR with mortality in COVID-19 patients. The study used an analytic observational method with a cross sectional approach from medical record data at UNS Hospital. The population in this study were COVID-19 patients at UNS Hospital who had their D-dimer and NLR levels checked in the period November 2020-January 2021. The sample was taken using a simple random sampling technique. Bivariate data analysis with Spearman Rank Correlation Test. Obtained 72 samples. 46 male patients and 26 female patients with the highest age range of 40-59 years as many as 34 patients. Patients who experienced mortality as many as 24 people while the rest survived. Spearman's Rank test obtained p-values of D-dimer and neutrophil lymphocyte ratio (NLR) with mortality of COVID-19 patients 0.009 and <0.001, respectively. While the correlation coefficients for D-dimer and NLR on mortality were 0.308 and 0.515, respectively. There is a relationship between D-dimer and NLR levels with mortality in COVID-19 patients with a positive correlation.


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How to Cite

Nurhayatun, E., Ayu Safira, M., & Nurudhin, A. (2023). The Correlation of D- Dimer and Neutrophil Lymphocyte Ratio (NLR) Levels on COVID-19 Mortality. JURNAL INFO KESEHATAN, 21(3), 428–437.



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